I have been taking Mercaptopurine for nearly a week now, in combination with injections of humira. It takes up to six weeks to see any effects from mercaptopurin. It is an immunosuppressive, and works by decreasing my white blood cell count, thus reducing inflammation throughout the body. One potential downside of this is that it is a bit like inducing anaemia, and can therefore make you very tired.
The past few days, I have indeed been very tired. I can't ever remember feeling so tired before! Well, at least not, when I have been trying to work at the same time! Obviously I was very sleepy immediately after my subtotal colectomy last year, but I could sleep all I wanted then as I was in hospital.
Trying to go to work, drive, hold intelligent conversation, look after two small children and do all my day to day tasks is incredibly difficult when you are feeling fatigued! I wonder what colleagues think of me when I am like this? It's not obvious that there is anything wrong with me, which means there isn't really any excuse or explanation if I don't do my work quickly or to a good standard.
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